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Schedule release: Betting odds for every Week 1 ga...

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May 14, 2026, 08:20 PM ETThe complete 2026 NFL schedule has been released, and odds are already available for Week 1 and several other high-profile games.The Seattle Seahawks and New England Patriots will meet in a Super Bowl rematch in the NFL's season opener on Wednesday, Sept. 9. The defending champion Seahawks opened as 3.5-point home favorites.The international series gets going Thursday, Sept. 10, with an NFC West matchup between the Los Angeles Rams -- the current favorites to win the Super Bowl -- and rival San Francisco 49ers in Melbourne, Australia.The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals. The Chargers are the only double-digit favorite. Nine games have spreads of a field goal or less.The highest points total in Week 1 is the Tampa Bay Buccaneers-Cincinnati Bengals matchup (50.5).Here's a look at the early odds for every Week 1 game, as well as other highlights on the schedule that already have spreads.Odds by DraftKings Sportsbook and subject to change.Wednesday, Sept. 9New England Patriots at Seattle Seahawks (-3.5) 8:20 p.m. ET on NBCMoneyline: Seahawks -192, Patriots +160 Total: 44.5 pointsThursday, Sept. 10San Francisco 49ers vs. Los Angeles Rams (-2.5) Melbourne Cricket Ground, Melbourne, Australia 8:35 p.m. ET on Netflix Moneyline: Rams -148, 49ers +124 Total: 48.5 pointsSunday, Sept. 13Chicago Bears (-2.5) at Carolina Panthers 1 p.m. ET on FOXMoneyline: Bears -135, Panthers +114 Total: 44.5 pointsTampa Bay Buccaneers at Cincinnati Bengals (3.5) 1 p.m. ET on FOXMoneyline: Bengals -198, Buccaneers +164 Total: 50.5 pointsCheck out all 32 teams' Super Bowl odds, win total projections and more.Baltimore Ravens (-3.5) at Indianapolis Colts 1 p.m. ET on CBSMoneyline: Ravens -185, Colts +154 Total: 49.5 pointsBuffalo Bills (-1.5) at Houston Texans 1 p.m. ET on CBSMoneyline: Bills -112, Texans -108 Total: 45.5 pointsNew Orleans Saints at Detroit Lions (-7) 1 p.m. ET on FOXMoneyline: Lions -325, Saints +260 Total: 48.5 pointsNew York Jets at Tennessee Titans (-3) 1 p.m. ET on CBSMoneyline: Titans -170, Jets +142 Total: 39.5 pointsAtlanta Falcons at Pittsburgh Steelers (-3) 1 p.m. ET on FOXMoneyline: Steelers -175, Falcons +145 Total: 42.5 pointsCleveland Browns at Jacksonville Jaguars (-7) 1 p.m. ET on CBSMoneyline: Jaguars -290, Browns +235 Total: 40.5 pointsFantasy football season is coming. Create or join an ESPN league today!Arizona Cardinals at Los Angeles Chargers (-11.5) 4:25 p.m. ET on CBSMoneyline: Chargers -625, Cardinals +455 Total: 45.5 pointsGreen Bay Packers (-1.5) at Minnesota Vikings 4:25 p.m. ET on CBSMoneyline: Packers -125, Vikings +105 Total: 44.5 pointsMiami Dolphins at Las Vegas Raiders (-3) 4:25 p.m. ET on FOXMoneyline: Raiders -175, Dolphins +145 Total: 41.5 pointsWashington Commanders at Philadelphia Eagles (-5.5) 4:25 p.m. ET on FOXMoneyline: Eagles -238, Commanders +195 Total: 46.5 points Dallas Cowboys (-2.5) at New York Giants 8:20 p.m. ET on NBCMoneyline: Cowboys -130, Giants +110 Total: 48.5 pointsMonday, Sept. 14Denver Broncos at Kansas City Chiefs (-2.5) 8:15 p.m. ET on ESPN/ABCMoneyline: Chiefs -155, Broncos +130 Total: 42.5 pointsplay0:39What Troy Aikman expects from Broncos-Chiefs looking ahead to Week 1Mike Greenberg and Troy Aikman weigh in on Broncos-Chiefs kicking off "Monday Night Football" for Week 1.Other highlighted games with odds available"Thursday Night Football"Sept. 17: Detroit Lions at Buffalo Bills (-3, 52.5), 8:15 p.m. ET (Prime Video)(First game at the new Highmark Stadium)Thanksgiving EveGreen Bay Packers at Los Angeles Rams (-3.5, 49.5), 8 p.m. ET (Netflix)Thanksgiving DayChicago Bears at Detroit Lions (-2.5, 51.5), 1 p.m. ET (CBS)Philadelphia Eagles (-1.5, 49.5) at Dallas Cowboys, 4:30 p.m. ET (FOX)Kansas City Chiefs at Buffalo Bills (-2.5, 49.5), 8:20 p.m. ET (NBC)Christmas DayGreen Bay Packers at Chicago Bears (-1.5, 47.5), 1 p.m. ET (Netflix)Los Angeles Rams at Seattle Seahawks (-1.5, 47.5), 8:15 p.m. ET (FOX)

Takes mentioned in this episode

  • Indianapolis Colts team · neutral
    “Baltimore Ravens (-3.5) at Indianapolis Colts”

    Listing the spread for the Ravens vs. Colts game.

  • Los Angeles Chargers team · positive
    “The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals. The Chargers are the only double-digit favorite.”

    Only double-digit favorite in Week 1 with largest spread

  • New England Patriots team · neutral
    “The Seattle Seahawks and New England Patriots will meet in a Super Bowl rematch...”

    Listing the first game of the NFL season opener.

  • Baltimore Ravens team · neutral
    “Baltimore Ravens (-3.5) at Indianapolis Colts”

    Listing the spread for the Ravens vs. Colts game.

  • Arizona Cardinals team · neutral
    “...favored by 11.5 points over the Arizona Cardinals.”

    Listing the spread for the Chargers vs. Cardinals game.

  • Seattle Seahawks team · positive
    “The defending champion Seahawks opened as 3.5-point home favorites.”

    Defending champions with home-field advantage in Super Bowl rematch

  • Arizona Cardinals team · negative
    “The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals.”

    Significant underdogs with largest spread against them in Week 1

  • Seattle Seahawks team · positive
    “The defending champion Seahawks opened as 3.5-point home favorites.”

    Discussing Week 1 odds and the Seattle Seahawks' status as defending champions.

  • Los Angeles Chargers team · neutral
    “The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points...”

    Highlighting the Chargers as a large favorite in their game against the Cardinals.

  • Cincinnati Bengals player · neutral
    “The highest points total in Week 1 is the Tampa Bay Buccaneers-Cincinnati Bengals matchup (50.5).”

    Identifying the high point total for a specific game.

  • Buffalo Bills team · neutral
    “Buffalo Bills (-1.5) at Houston Texans”

    Listing the spread for the Bills vs. Texans game.

  • Tampa Bay Buccaneers team · neutral
    “The highest points total in Week 1 is the Tampa Bay Buccaneers-Cincinnati Bengals matchup (50.5).”

    Identifying the high point total for a specific game.

  • San Francisco 49ers team · neutral
    “...rival San Francisco 49ers in Melbourne, Australia.”

    Listing the international series matchup between Rams and 49ers.

  • Los Angeles Rams team · positive
    “...the Los Angeles Rams -- the current favorites to win the Super Bowl...”

    Describing the Rams as the current Super Bowl favorites.

  • Houston Texans team · neutral
    “Buffalo Bills (-1.5) at Houston Texans”

    Listing the spread for the Bills vs. Texans game.

  • Los Angeles Rams team · positive
    “The international series gets going Thursday, Sept. 10, with an NFC West matchup between the Los Angeles Rams -- the current favorites to win the Super Bowl -- and rival San Francisco 49ers in Melbourne, Australia.”

    Current Super Bowl favorites heading into season

  • New York Jets team · neutral
    “New York Jets at Tennessee Titans (-3) 1 p.m. ET on CBSMoneyline: Titans -170, Jets +142 Total: 39.5 points”

    New York Jets at Tennessee Titans (-3) 1 p.m. ET on CBSMoneyline: Titans -170, Jets +142 Total: 39.5 points

  • Detroit Lions team · neutral
    “New Orleans Saints at Detroit Lions (-7) 1 p.m. ET on FOXMoneyline: Lions -325, Saints +260 Total: 48.5 points”

    New Orleans Saints at Detroit Lions (-7) 1 p.m. ET on FOXMoneyline: Lions -325, Saints +260 Total: 48.5 points

  • Tampa Bay Buccaneers team · neutral
    “Tampa Bay Buccaneers at Cincinnati Bengals (3.5) 1 p.m. ET on FOXMoneyline: Bengals -198, Buccaneers +164 Total: 50.5 points”

    Tampa Bay Buccaneers at Cincinnati Bengals (3.5) 1 p.m. ET on FOXMoneyline: Bengals -198, Buccaneers +164 Total: 50.5 points

  • New Orleans Saints team · neutral
    “New Orleans Saints at Detroit Lions (-7) 1 p.m. ET on FOXMoneyline: Lions -325, Saints +260 Total: 48.5 points”

    New Orleans Saints at Detroit Lions (-7) 1 p.m. ET on FOXMoneyline: Lions -325, Saints +260 Total: 48.5 points

  • Las Vegas Raiders team · neutral
    “Miami Dolphins at Las Vegas Raiders (-3) 4:25 p.m. ET on FOXMoneyline: Raiders -175, Dolphins +145 Total: 41.5 points”

    Miami Dolphins at Las Vegas Raiders (-3) 4:25 p.m. ET on FOXMoneyline: Raiders -175, Dolphins +145 Total: 41.5 points

  • Houston Texans team · neutral
    “Buffalo Bills (-1.5) at Houston Texans 1 p.m. ET on CBSMoneyline: Bills -112, Texans -108 Total: 45.5 points”

    Buffalo Bills (-1.5) at Houston Texans 1 p.m. ET on CBSMoneyline: Bills -112, Texans -108 Total: 45.5 points

  • Arizona Cardinals team · neutral
    “The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals.”

    The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals.

  • Washington Commanders team · neutral
    “Washington Commanders at Philadelphia Eagles (-5.5) 4:25 p.m. ET on FOXMoneyline: Eagles -238, Commanders +195 Total: 46.5 points”

    Washington Commanders at Philadelphia Eagles (-5.5) 4:25 p.m. ET on FOXMoneyline: Eagles -238, Commanders +195 Total: 46.5 points

  • Philadelphia Eagles team · neutral
    “Washington Commanders at Philadelphia Eagles (-5.5) 4:25 p.m. ET on FOXMoneyline: Eagles -238, Commanders +195 Total: 46.5 points”

    Washington Commanders at Philadelphia Eagles (-5.5) 4:25 p.m. ET on FOXMoneyline: Eagles -238, Commanders +195 Total: 46.5 points

  • Dallas Cowboys team · neutral
    “Dallas Cowboys (-2.5) at New York Giants 8:20 p.m. ET on NBCMoneyline: Cowboys -130, Giants +110 Total: 48.5 points”

    Dallas Cowboys (-2.5) at New York Giants 8:20 p.m. ET on NBCMoneyline: Cowboys -130, Giants +110 Total: 48.5 points

  • New York Giants team · neutral
    “Dallas Cowboys (-2.5) at New York Giants 8:20 p.m. ET on NBCMoneyline: Cowboys -130, Giants +110 Total: 48.5 points”

    Dallas Cowboys (-2.5) at New York Giants 8:20 p.m. ET on NBCMoneyline: Cowboys -130, Giants +110 Total: 48.5 points

  • Denver Broncos team · neutral
    “Denver Broncos at Kansas City Chiefs (-2.5) 8:15 p.m. ET on ESPN/ABCMoneyline: Chiefs -155, Broncos +130 Total: 42.5 points”

    Denver Broncos at Kansas City Chiefs (-2.5) 8:15 p.m. ET on ESPN/ABCMoneyline: Chiefs -155, Broncos +130 Total: 42.5 points

  • Kansas City Chiefs team · neutral
    “Denver Broncos at Kansas City Chiefs (-2.5) 8:15 p.m. ET on ESPN/ABCMoneyline: Chiefs -155, Broncos +130 Total: 42.5 points”

    Denver Broncos at Kansas City Chiefs (-2.5) 8:15 p.m. ET on ESPN/ABCMoneyline: Chiefs -155, Broncos +130 Total: 42.5 points

  • Los Angeles Rams team · neutral
    “San Francisco 49ers vs. Los Angeles Rams (-2.5) Melbourne Cricket Ground, Melbourne, Australia 8:35 p.m. ET on Netflix Moneyline: Rams -148, 49ers +124 Total: 48.5 points”

    San Francisco 49ers vs. Los Angeles Rams (-2.5) Melbourne Cricket Ground, Melbourne, Australia 8:35 p.m. ET on Netflix Moneyline: Rams -148, 49ers +124 Total: 48.5 points